C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/134
C12P 41/00 (2006.01) C12N 9/10 (2006.01) C12P 7/26 (2006.01)
Patent
CA 2018773
Amines in which the amino group is on a secondary carbon atom which is chirally substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other.
Matcham George W.
Stirling David I.
Zeitlin Andrew L.
Celgene Corporation
Gowling Lafleur Henderson Llp
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