Enantiomeric hydroxylated xanthine compounds

Details Enantiomeric hydroxylated xanthine compounds Enantiomeric hydroxylated xanthine compounds

A - Human Necessities

61

K

A61K 31/52 (2006.01) C07D 473/10 (2006.01)

Patent

CA 2112239

There is disclosed compounds and pharmaceutical compositions that are a resolved R or S (preferably R) enantiomer of an w-1 alcohol of a straight chain alkyl (C5-8) substituted at the 1-position of 3,7-disubstituted xanthine. The inventive compounds are effective in modulating cellular response to external or in situ primary stimuli, as well as to specific modes of administration of such.

On décrit des composés et des compositions pharmaceutiques qui constituent un énantiomère dédoublé R (de préférence) ou S d'un alcool w-1 d'un alkyle à chaîne droite (C5-8) substitué à la position 1 de la xanthine substituée aux positions 3-7. Les composés inventés sont efficaces pour moduler des réactions cellulaires à des stimuli primaires externes ou in situ, ou à des modes d'administration spécifiques les concernant.

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