Enantiomers of 3-heteroaryl-8h-8-azabicyclo(3.2.1)oct-2-ene...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/04 (2006.01) A61K 31/46 (2006.01) A61P 25/16 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 25/32 (2006.01) A61P 25/34 (2006.01) A61P 25/36 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2591621

This invention relates to novel enantiomers of 3-heteroaryl-8H-8azabicyclo- [3.2.1] oct-2-ene useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

La présente invention a pour objet de nouveaux énantiomères de 3-hétéroaryl-8H-8-azabicyclo-(3.2.1)-oct-2-ène pouvant être employés en tant qu'inhibiteurs du recaptage de neurotransmetteurs de type monoamine. Dans d'autres aspects, l'invention concerne l'utilisation de ces composés dans une méthode thérapeutique, ainsi que des préparations pharmaceutiques incluant les composés de l'invention.

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