Enantioselective synthesis of antifolates

C - Chemistry – Metallurgy – 07 – D

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260/491, 260/242

C07D 471/04 (2006.01) C07C 69/007 (2006.01) C07C 69/16 (2006.01) C07C 247/10 (2006.01) C07D 211/78 (2006.01)

Patent

CA 2020340

A process and intermediates of the formula (see formula I) for the enantioselective synthesis of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid are disclosed.

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