Encapsulated agglomeration of microcapsules and method for...

A - Human Necessities – 23 – L

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A23L 1/00 (2006.01) A23L 1/30 (2006.01) A23P 1/04 (2006.01) A61K 9/50 (2006.01) A61K 9/54 (2006.01) A61K 9/56 (2006.01) B01J 13/10 (2006.01)

Patent

CA 2455971

Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be prepared by providing an aqueous mixture of a loading substance and a shell material, adjusting pH, temperature, concentration and/or mixing speed to form primary shells of shell material around the loading substance and cooling the aqueous mixture until the primary shells agglomerate and an outer shell of shell material forms around the agglomeration. Such microcapsules are useful for storing a substance and for delivering the substance to a desired environment.

Microcapsules comprenant une agglomération de microcapsules primaires dont chacune comprend une enveloppe primaire et une agglomération encapsulée par une capsule externe, qui peuvent être fabriquées par la préparation d'un mélange aqueux d'une substance de charge et d'un matériau d'enveloppe, par l'ajustement du pH, de la température, de la concentration et/ou de la vitesse de mélangeage afin de former des enveloppes primaires faites d'un matériau d'enveloppe autour de la substance de charge et par le refroidissement du mélange aqueux jusqu'à l'agglomération de l'enveloppe primaire suivie de la formation d'une enveloppe du matériau d'enveloppe autour de l'agglomération. Ces microcapsules sont utiles pour le stockage d'une substance et l'administration de la substance dans un environnement désiré.

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