Encapsulated cell indicator system

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/04 (2006.01) A01K 67/027 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) C12N 5/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2443984

The invention features an encapsulated cell indicator system that includes: a) indicator cells having a signal-responsive element operably linked to a reporter gene; b) encapsulating material; and c) a permeable membrane. In this encapsulated cell indicator system, the indicator cells are encapsulated in the encapsulated material and the encapsulated material and the indicator cells are surrounded by the permeable membrane.

L'invention concerne un système indicateur pour cellules encapsulées qui comprend : a) des cellules indicatrices comportant un élément sensible aux signaux relié fonctionnellement à un gène rapporteur ; b) un matériau d'encapsulation ; et c) une membrane perméable. Dans ce système indicateur pour cellules encapsulées, les cellules indicatrices sont encapsulées dans le matériau encapsulé tandis que le matériau encapsulé et les cellules indicatrices sont entourées par la membrane perméable.

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