Encapsulated kidney tissue

Details Encapsulated kidney tissue Encapsulated kidney tissue

A - Human Necessities

61

L

A61L 27/22 (2006.01) A61L 27/36 (2006.01)

Patent

CA 2708959

Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a subject comprising implanting within said subject a therapeutic implant comprising renal tissue encapsulated within a polymer bead. Also provided are methods for making a therapeutic implant comprising: providing renal tissue; mixing the renal tissue with a solution comprising a polymer, thereby forming a tissue-polymer suspension; extruding the tissue-polymer suspension into an bead-forming solution, thereby forming a therapeutic implant comprising beads of said polymer within which the renal tissue is encapsulated.

L'invention concerne des implants thérapeutiques qui comprennent du tissu rénal encapsulé dans une bille de polymère. L'invention concerne également des méthodes de traitement d'un état maladif chez un sujet, lesquelles comprennent l'implantation dans ledit sujet d'un implant thérapeutique qui comprend du tissu rénal encapsulé dans une bille de polymère. L'invention concerne également des procédés de fabrication d'un implant thérapeutique qui comprennent : l'utilisation d'un tissu rénal; le mélange du tissu rénal avec une solution comprenant un polymère, formant ainsi une suspension tissu-polymère; l'extrusion de la suspension tissu-polymère dans une solution de formation de billes, formant ainsi un implant thérapeutique comprenant des billes dudit polymère, à l'intérieur desquelles le tissu rénal est encapsulé.

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