Encapsulated particles useful as contrast agents in...

Details Encapsulated particles useful as contrast agents in... Encapsulated particles useful as contrast agents in...

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 49/22 (2006.01)

Patent

CA 2083109

ENCAPSULATED PARTICLES USEFUL AS CONTRAST AGENTS IN ULTRASOUND AND X-RAY IMAGING COMPOSITIONS AND METHODS Abstract Stable particles comprising a core consisting of a water-insoluble ester or amide of 3,5-diacetamido- 2,4,6-triiodobenzoic acid encapsulated with methyl cellulose, such particles having an average particle size of less than about 10 µm, dispersions containing such particles, and methods for the preparation thereof are disclosed. The particles are particularly useful as contrast agents for use in x-ray and ultrasound diagnostic imaging compositions and methods.

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