Encapsulated picoplatin

Details Encapsulated picoplatin Encapsulated picoplatin

A - Human Necessities

61

K

A61K 33/24 (2006.01) A61K 9/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2677639

The invention provides an encapsulated unit dosage form for picoplatin that is adapted for oral administration of the picoplatin containing a substantially dry powder with about 20 to 55 wt% picoplatin in the physical form of a picoplatin particulate wherein an average picoplatin particle diameter is less than about 10 microns. The picoplatin particles are dispersed within the powder of the formulation which includes a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate and an effective amount of up to about 5 wt% of a lubricant.

L'invention concerne une forme posologique unitaire encapsulée de picoplatine qui est conçue pour une administration par voie orale du picoplatine, contenant une poudre sensiblement sèche présentant environ 20 à 55% en poids de picoplatine sous la forme physique de particules de picoplatine, le diamètre moyen des particules de picoplatine étant inférieur à environ 10 microns. Les particules de picoplatine sont dispersées dans la poudre de la préparation qui comprend un hydrate de carbone sensiblement hydrosoluble, hydrodispersable ou absorbant l'eau et une quantité efficace pouvant s'élever jusqu'à environ 5 % en poids d'un lubrifiant.

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