End-attachment of oligonucleotides to polyacrylamide solid...

Details End-attachment of oligonucleotides to polyacrylamide solid... End-attachment of oligonucleotides to polyacrylamide solid...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2044173

2044173 9007582 PCTABS00001 This invention concerns methods and means for covalent attachment of oligonucleotides to solid supports substantially at their 5'-ends. According to the invention thio-oligonucleotides are attached to bromoacetyl-derivatized polyacrylamide supports, or conversely, bromoacetyl-oligonucleotides are immobilized on thiol-polyacrylamide supports. In a further aspect, this invention relates to bromoacetyl-oligonucleotides that may be immobilized on thiol-polyacrylamide solid supports, thiol-oligonucleotides immobilized on bromoacetyl-derivatized polyacrylamide supports as well as to methods for capture of nucleic acids by oligonucleotides attached to polyacrylamide solid supports, either by direct capture or in sandwich hybridization formats.

Affiliated with

Also associated with

Rating

End-attachment of oligonucleotides to polyacrylamide solid... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with End-attachment of oligonucleotides to polyacrylamide solid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and End-attachment of oligonucleotides to polyacrylamide solid... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1897660