Endocrine pancreas differentiation of adipose tissue-derived...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/077 (2010.01) A61K 35/39 (2006.01) A61L 27/38 (2006.01) C12P 21/00 (2006.01) C12P 33/00 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2465950

The invention provides cells, compositions and methods based on the differentiation of adipose tissue-derived stromal cells into a cell expressing at least one genotypic or phenotypic characteristic of a pancreas cell. The cells produced in the method are useful in providing a source of differentiated and functional cells for research, implantation, transplantation and development of tissue engineered products for the treatment of diseases of the pancreas and pancreatic tissue repair.

L'invention concerne des cellules, des compositions et des méthodes se fondant sur la différenciation des cellules stromales dérivées du tissu adipeux en une cellule exprimant au moins une caractéristique génotypique ou phénotypique d'une cellule du pancréas. Les cellules produites au moyen de ces méthodes sont utiles pour l'obtention d'une source de cellules différenciées et fonctionnelles pour la recherche, l'implantation, la transplantation et le développement de produits obtenus par génie tissulaire aux fins de traitement des maladies du pancréas et de réparation du tissu pancréatique.

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