Endogenetic nucleic fragment associated with an autoimmune...

Details Endogenetic nucleic fragment associated with an autoimmune... Endogenetic nucleic fragment associated with an autoimmune...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07K 14/15 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2358926

The invention concerns an endogenetic nucleic fragment, such as an isolated retrovirus, integrated in the human DNA genome, said fragment being characterised in that it comprises, or consists of, at least part of the gag gene of an endogenetic retrovirus associated with an autoimmune disease or pregnancy failure or pregnancy pathologies, said part at least coding, directly or indirectly, for an expression product, or the complementary of said fragment.

Fragment nucléique endogène, de type rétroviral, à l'état isolé, et intégré à l'ADN du génome humain, ledit fragment étant caractérisé en ce qu'il comprend, ou consiste en, au moins une partie du gène gag d'un rétrovirus endogène associé à une maladie auto-immune ou à des insuccès de grossesse ou pathologies de la grossesse, ladite partie au moins codant, directement ou indirectement, pour un produit d'expression, ou le complémentaire dudit fragment.

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