Endogenetic retroviral sequences, associated with autoimmune...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/48 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2298834

The invention concerns a genomic retroviral nucleic material, in isolated or purified state, at least partially functional or non-functional, whereof the genome comprises a reference nucleotide sequence selected from the group including sequences SEQ ID N?os¿: 1 to 15, their complementary sequences, and their equivalent sequences, in particular the nucleotide sequences having, for every series of 100 contiguous monomers, at least 70 % and preferably at least 90 % homology with said sequences SEQ ID N?os¿: 1 to 15. The invention also concerns the application of said material.

L'invention concerne un matériel nucléique de type génomique rétroviral, à l'état isolé ou purifié, au moins partiellement fonctionnel ou non fonctionnel, dont le génome comprend une séquence nuclééotidique de référence choisie dans le groupe incluant les séquences SEQ ID NOs: 1 à 15, leurs séquences complémentaires, et leurs séquences équivalentes, notamment les séquences nucléotidiques présentant, pour toute suite de 100 monomères contigus, au moins 70 % et préférentiellement au moins 90 % d'homologie avec respectivement lesdites séquences SEQ ID NOs: 1 à 15; et les applications de ce matériel.

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