Endogenous and non-endogenous versions of human g...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2429860

The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown, and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.

Cette invention concerne des récepteurs transmembranaires, et plus particulièrement un récepteur couplé aux protéines G humaines pour lequel le ligand endogène est inconnu. Elle concerne également des versions mutantes (non endogènes) des GPCR pour des signes d'activité constitutive.

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