Endogenous auto-fluorescent biological markers for assessing...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/02 (2006.01) C12N 1/00 (2006.01) C12N 5/00 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2739730

The present application relates to the use of endogenous fluorescent biological markers to determine a biological parameter of a cell in a liquid. The methods provided herein provide accurate results in a relatively short amount of time and can be used to monitor and optimize cell culture online as well as determining the presence of a cellular contamination in a cell suspension.

La présente invention concerne l'utilisation de marqueurs biologiques fluorescents endogènes pour déterminer un paramètre biologique d'une cellule dans un liquide. Les procédés de la présente invention fournissent des résultats précis sur une durée relativement courte et peuvent être utilisés pour surveiller et optimiser une culture cellulaire en ligne ainsi que pour déterminer la présence d'une contamination cellulaire dans une suspension de cellules.

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