Endometriosis-related markers and uses thereof

Details Endometriosis-related markers and uses thereof Endometriosis-related markers and uses thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2399259

The present invention relates to markers of endometriosis which are differentially expressed in the endometrial cells of females with endometriosis compared to endometriosis-free females. The invention also relates to methods for determining likelihood of endometriosis in female subjects, to methods for grading endometriosis in females suffering from endometriosis and to methods for treating this disease. The invention is also concerned with polynucleotides, probes, primers and kits useful for reducing into practice the above-mentioned methods which are more rapid, non invasive, much less complicated and much less costly than laparoscopy.

L'invention concerne des marqueurs de l'endométriose exprimés de manière différentielle dans les cellules endométriales de femelles atteintes de l'endométriose comparées à des femelles non-affectées. L'invention concerne également des procédés de détermination de la similitude de l'endométriose chez des sujets femelles, des procédés permettant d'évaluer l'endométriose chez des femelles atteintes et enfin des procédés pour traiter cette affection. L'invention concerne encore des polynucléotides, des sondes, des amorces et des dispositifs utilisés pour appliquer les procédés susmentionnés qui sont plus rapides, non-invasifs et surtout beaucoup moins compliqués et moins coûteux que la laparoscopie.

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