C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A61K 47/48 (2006.01) C07K 19/00 (2006.01) C12N 7/04 (2006.01) C12N 15/62 (2006.01)
Patent
CA 2172139
Endosomolytically active virus-like particle which is made up of units of capsid proteins of viruses or virus- like particles, the capsid protein units having a membrane-active peptide sequence. The particles are suitable as components of compositions for transporting nucleic acids into higher eukaryotic cells by receptor- mediated endocytosis.
Une particule de type viral à activité endosomolytique se compose d'unités de protéines de capside de virus ou de particules de type viral, ces unités protéiques de capside présentant une séquence peptidique à activité membranaire. Ces particules conviennent comme constituant de compositions permettant le transport d'acides nucléiques dans des cellules eucaryotes supérieures par l'intermédiaire d'endocytoses transmises par des récepteurs.
Chiocca Susanna
Cotten Matthew
Schaffner Gotthold
Wagner Ernst
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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