Endothelial cell apoptosis induced by fibrinogen gamma chain...

Details Endothelial cell apoptosis induced by fibrinogen gamma chain... Endothelial cell apoptosis induced by fibrinogen gamma chain...

C - Chemistry, Metallurgy

12

P

C12P 21/06 (2006.01)

Patent

CA 2565794

The present invention provides for the novel use of a polypeptide related to a fibrinogen chain C-terminal fragment or a nucleic acid encoding the polypeptide for inhibiting endothelial cell proliferation. Methods of using the polypeptide or the nucleic acid are provided. Also provided are compositions containing the polypeptide or the nucleic acid and kits containing the compositions.

La présente invention concerne la nouvelle utilisation d'un polypeptide apparenté à un fragment C-terminal de la chaîne gamma du fibrinogène, ou d'un acide nucléique codant le polypeptide pour inhiber la prolifération des cellules endothéliales. Elle concerne également des méthodes d'utilisation du polypeptide ou de l'acide nucléique. Elle concerne en outre des compositions contenant le polypeptide ou l'acide nucléique, et des trousses contenant ces compositions.

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