Endothelial cell proliferation inhibitor and method of use

Details Endothelial cell proliferation inhibitor and method of use Endothelial cell proliferation inhibitor and method of use

A - Human Necessities

61

K

A61K 38/48 (2006.01) C12N 9/68 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2240296

The present invention comprises an endothelial inhibitor and method of use therefor. The endothelial cell proliferation inhibitor is a protein having a molecular weight of approximately 14 KD and having an N- terminal sequence of GPVGAGEPKCPLMVKVLDAV, that has the ability to inhibit endothelial cell proliferation in in vitro assays.

La présente invention concerne un inhibiteur endothélial ainsi qu'un procédé d'utilisation de celui-ci. Cet inhibiteur de la prolifération des cellules endothéliales consiste en une protéine possédant un poids moléculaire d'environ 14 kD ainsi qu'une séquence N-terminale GPVGAGEPKCPLMVKVLDAV, cette protéine étant capable d'inhiber la prolifération cellulaire endothéliale dans des dosages in vitro.

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