Endothelial cells as diagnostic instrument in cardiovascular...

Details Endothelial cells as diagnostic instrument in cardiovascular... Endothelial cells as diagnostic instrument in cardiovascular...

G - Physics

01

N

G01N 33/50 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2506046

The invention relates to a method for the immunocytological determination of apoptotic endothelial cells and/or endothelial precursor cells in samples such as, for example, peripheral blood, by means of, for example, throughflow cytometry or by means of a solid-phase immunoassay, as a diagnostic instrument in patients in whom a cardiovascular disease is either manifest or who carry the risk for the same and as an instrument by means of which the prevention and the therapeutic management of such a disease can be improved.

L'invention concerne un procédé d'analyse immunocytologique de cellules endothéliales apoptotiques et/ou de cellules précurseurs endothéliales dans des échantillons tels que de sang périphérique, p. ex. par cytométrie de flux ou par immuno-essai en phase solide, comme instrument de diagnostic chez des patients souffrant manifestement d'une maladie cardiovasculaire ou présentant un risque de développer une telle maladie et comme un instrument permettant d'améliorer la prévention et la gestion thérapeutique d'une maladie de ce type.

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