Endothelin antagonist and beta receptor blocking agent as...

Details Endothelin antagonist and beta receptor blocking agent as... Endothelin antagonist and beta receptor blocking agent as...

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2304698

The invention relates to a combination consisting of endothelin antagonists of formula: and beta receptor blocking agents. Said combination is suitable for the treatment of diseases such as those diseases based on vasoconstriction or associated with pathological vasoconstriction, all forms of high blood pressure, coronary heart disease, cardiac insufficiency, renal ischemia, myocardiac ischemia, acute renal insufficiency, chronic renal insufficiency, pulmonary hypertension, asthma, migraine, brain ischemia, gastrointestinal tract ischemia, liverischemia, vasospasms, dialysis, subarachnoidal haemorrhage, Raynaud's syndrome, portal high pressure, gastric ulcer, duodenal ulcer, stasis ulcer and cardiovascular disorders.

L'invention concerne une association d'antagonistes d'endothéline et de bêta-bloquants. Cette association convient au traitement de maladies.

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