C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/08 (2006.01) C07K 5/107 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2146874
Novel antagonists of endothelin are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in treating elevated levels of endothelin, acute and chronic renal failure, hypertension, myocardial infarction, metabolic, endocrinological, neurological disorders, congestive heart failure, endotoxic shock, subarachnoid, hemorrhage, arrhythmias, asthma, preeclampsia Raynaud's disease, percutaneous transluminal coronary angioplasty or restenosis, angina, cancer, pulmonary hypertension, ischemic disease, gastric mucosal damage, ischemic bowel disease, and diabetes.
Cody Wayne Livingston
Depue Patricia
Doherty Annette Marian
He John Xiaoqiang
Taylor Michael Douglas
Macrae & Co.
Warner-Lambert Company
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