Endothelin antagonists

Details Endothelin antagonists Endothelin antagonists

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 5/107 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2108754

2108754 9220706 PCTABS00017 Novel antagonists of endothelin are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling hypertension, myocardial infarction, metabolic, endocrinological, and neurological disorders, congestive heart failure, endotoxic shock, subarachnoid hemorrhage, arrythmias, asthma, acute renal failure, preeclampsia, and diabetes.

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