Endothelin precursors, genes and receptors

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/575 (2006.01) C07K 14/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2053650

ABSTRACT The amino acid and nucleotide sequences of the precursor molecules for endothelin-2 and endothelin-3 are provided. Further, the purification and cloning of the receptors for ET-1, ET-2, and ET-3 are described. The compositions find use in regulating vascular activities. A118-06.WP5 101790

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