Endothelium mimicking nanomatrix

Details Endothelium mimicking nanomatrix Endothelium mimicking nanomatrix

C - Chemistry, Metallurgy

07

K

C07K 2/00 (2006.01) A61K 9/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61L 31/08 (2006.01) A61P 9/10 (2006.01) C07K 1/107 (2006.01) C07K 5/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01)

Patent

CA 2742782

Disclosed herein are peptide amphiphiles for use in producing a natural endothelium mimicking nanomatrix. The disclosed natural endothelium mimicking nanomatrix can be used to coat medical devices such as vascular stents to promote endothelializaiton and inhibit restenosis and thrombosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Les amphiphiles peptidiques ci-décrits peuvent être utilisés pour produire une nanomatrice imitant l'endothélium naturel. La nanomatrice imitant l'endothélium naturel décrite peut être utilisée pour revêtir des dispositifs médicaux tels que des endoprothèses vasculaires afin de favoriser l'endothélialisation et d'inhiber la resténose et la thrombose. Le présent abrégé est à considérer comme un outil d'exploration destiné à investiguer l'art particulier et ne vise pas à limiter la présente invention.

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