A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 2/00 (2006.01) A61M 1/36 (2006.01) B01D 67/00 (2006.01) B01J 20/32 (2006.01) B01D 15/38 (2006.01)
Patent
CA 2486563
An affinity ligand-matrix conjugate of the structure Z-Spacer-~NX-A~m- NY-A- NX2 is useful for the isolation, separation, purification, characterization, identification or quantification of endotoxins in an aqueous system, wherein m is an integer of at least one; each A independently represents an optionally substituted linear, branched or cyclic saturated hydrocarbon chain containing 1 to 6 carbon atoms; each X independently represents hydrogen or alkyl; Y is X or A-NX2; and Z is a support matrix attached to the ligand through an optional spacer arm (Spacer).
La présente invention concerne un conjugué ligand d'affinité-matrice de la structure Z-Bras écarteur-ÝNX-A¨¿m?- NY-A-NX¿2? qui est utilisé pour isoler, séparer, purifier, caractériser, identifier ou quantifier des endotoxines dans un système aqueux, où m est un entier égal au moins à un ; chaque A représente indépendamment une chaîne hydrocarbonée saturée linéaire, ramifiée ou cyclique facultativement substituée contenant de 1 à 6 atomes de carbone ; chaque X représente indépendamment un hydrogène ou un alkyle ; Y est X ou A-NX¿2 ?; et Z est une matrice de support attachée au ligand via un bras écarteur facultatif.
Burton Steven James
Eapen Saji S.
Podgorski Tadeusz
Prometic Biosciences Ltd
Torys Llp
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