Engineered extracellular matrices

Details Engineered extracellular matrices Engineered extracellular matrices

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61L 27/36 (2006.01)

Patent

CA 2608708

The invention relates to engineered matrices comprising collagen fibrils with specific characteristics, including, but not limited to, a specific fibril area fraction (i.e., density) and/or a specific elastic or linear modulus (i.e., stiffness). The invention also relates to methods of preparation and use of the matrices.

L'invention concerne des matrices manipulées comprenant des fibrilles de collagène avec des caractéristiques spécifiques, notamment mais sans caractère restrictif : un frottement de zone de fibrille spécifique (par exemple, la densité) et/ou un module élastique ou linéaire spécifique (par exemple, la rigidité). L'invention concerne également des procédés de préparation et d'utilisation des matrices.

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