Engineered extracellular matrices control stem cell behavior

Details Engineered extracellular matrices control stem cell behavior Engineered extracellular matrices control stem cell behavior

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2608422

A composition for culturing stem cells is provided. The composition comprises an engineered purified collagen based matrix that has been formed under controlled conditions to have the desired microstructure and mechanical properties. The engineered purified collagen based matrix compositions of the present invention can be used alone or in combination with cells as a tissue graft construct to enhance the repair of damaged or diseased tissues.

L'invention concerne une composition permettant la culture de cellules souches. Cette composition comprend une matrice de synthèse à base de collagène purifié, qui a été formée dans des conditions contrôlées, de manière à présenter la microstructure et les caractéristiques mécaniques recherchées. Ces compositions de matrice de synthèse à base de collagène purifié peuvent être utilisées seules ou combinées à des cellules, en tant que greffon tissulaire reconstitué, pour favoriser la réparation de tissus endommagés ou malades.

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