Engineered muscle

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/50 (2006.01) A61F 2/06 (2006.01) A61F 2/08 (2006.01) A61L 27/18 (2006.01) A61L 27/24 (2006.01) A61L 27/34 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2383145

A muscle implant includes an extracellular matrix, tendon and muscle cells. The extracellular matrix is made of a matrix of electroaerosol and/or electrospun polymer droplets. Cardiac and smooth muscles may be formed by depositing an extracellular matrix onto a mandrel, the extracellular matrix comprising a polymer helically wound around the mandrel at predetermined pitches.

L'invention concerne un implant musculaire qui comprend une matrice extracellulaire, un tendon et des cellules musculaires. La matrice extracellulaire est constituée d'une matrice de gouttelettes de polymère pulvérisées électriquement et/ou électrofilées. Des muscles cardiaques ou des muscles lisses peuvent être formés par dépôt d'une matrice extracellulaire sur un mandrin, ladite matrice extracellulaire comprenant un polymère ondulé hélicoïdal disposé autour du mandrin à des pas préétablis.

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