Engineered secreted alkaline phosphatase (seap) reporter...

Details Engineered secreted alkaline phosphatase (seap) reporter... Engineered secreted alkaline phosphatase (seap) reporter...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2448145

The invention provides a novel reporter gene (mSEAP) capable of being expressed in a mammal for extended periods of time. Nucleic acids encoding the reporter gene, cells and vectors comprising the nucleic acids, and methods of using the reporter gene to identify expression vectors and screen for drug compounds in an animal are also disclosed.

L'invention concerne un nouveau gène reporter (mSEAP) capable d'être exprimé dans un mammifère pendant des périodes de temps étendues. L'invention concerne en outre des acides nucléiques codant pour ce gène, des cellules et des vecteurs comprenant les acides nucléiques, ainsi que des procédés d'utilisation de ce gène en vue d'identifier des vecteurs d'expression et de dépister des composés de médicaments dans un animal.

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