Engineered versions of polysialyltransferases with enhanced...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/10 (2006.01) C12P 7/64 (2006.01) C12P 19/00 (2006.01) C12P 19/18 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2689557

The invention relates to poly-sialyltransferase polypeptides with enhanced solubility and activity and methods of using the poly-sialyltransferases for production of poly-sialylated end products, e.g., oligosaccharides, glycoproteins and glycolipids.

L'invention porte sur des polypeptides de polysialyltransférase avec une meilleure solubilité et une meilleure activité et sur des procédés d'utilisation des polysialyltransférases pour une fabrication de produits finaux polysialylés, par exemple, des oligosaccharides, des glycoprotéines et des glycolipides.

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