Engineering fungi for the utilisation of l-arabinose

Details Engineering fungi for the utilisation of l-arabinose Engineering fungi for the utilisation of l-arabinose

C - Chemistry, Metallurgy

12

N

C12N 1/14 (2006.01) C12N 9/04 (2006.01) C12P 7/00 (2006.01)

Patent

CA 2405883

A fungal microorganism can be engineered by means of genetic engineering to utilise L-arabinose. The genes of the L-arabinose pathway, which were unknown, i.e. L-arabinitol 4-dehydrogenase and L-xylulose reductase, were identified. These genes, together with the known genes of the L-arabinose pathway, form a functional pathway. This pathway can be introduced to a fungus, which is completely or partially lacking this pathway.

On obtient par génie génétique un micro-organisme fongique destiné à l'utilisation de L-arabinose. Dans cette invention, on a identifié les gènes de la voie de conduction de L-arabinose, jusqu'à maintenant inconnues, à savoir L-arabinitol 4-déshydrogénase et L-xylulose réductase. Ces gènes, conjointement avec les gènes connus de la voie de conduction de L-arabinose, forment une voie de conduction fonctionnelle. Cette voie de conduction peut être introduite dans un champignon auquel elle fait défaut, totalement ou en partie.

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