Enhanced absorption of modified release dosage forms

A - Human Necessities – 61 – K

Patent

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A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2550983

Disclosed are products and methods for improving the plasma profile in a patient being treated with a pharmaceutical active agent that is subject to a limited window of absorption, which products and methods comprise orally administering the active agent in multiparticulate form, such that at least a portion thereof is delivered to the intestine while the patient is in the fed condition.

L'invention concerne des produits et des méthodes destinés à améliorer le profil plasmatique chez un patient traité avec un agent actif d'un point de vue pharmaceutique soumis à un degré limité d'absorption, lesdits produits et méthodes étant associés à l'administration orale de l'agent actif sous forme multiparticulaire, de manière qu'au moins une partie de celui-ci soit délivrée à l'intestin tandis que le patient est alimenté.

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