Enhanced circulation effector composition and method

A - Human Necessities – 61 – K

Patent

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A61K 9/127 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2157410

A liposome composition comprising small, surface-bound effector surface-bound is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.

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