Enhanced functional expression of g protein-coupled receptors

Details Enhanced functional expression of g protein-coupled receptors Enhanced functional expression of g protein-coupled receptors

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/395 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 1/19 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/67 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2343046

This invention relates to constitutively active mutant G protein-coupled receptors, yeast cell expressing such receptors, vectors useful for making such cells, and methods of making and using same.

L'invention concerne des récepteurs mutants couplés à la protéine G, lesquels exercent une action constitutive. L'invention concerne également des cellules de levure exprimant ces récepteurs, des vecteurs convenant à la fabrication de ces cellules et des méthodes de fabrication et d'utilisation associées.

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