C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/01 (2006.01) A61K 31/70 (2006.01) A61K 35/76 (2006.01) A61K 48/00 (2006.01) C07K 14/54 (2006.01) C07K 14/55 (2006.01) C07K 14/705 (2006.01) C12N 7/04 (2006.01) C12N 15/863 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2201592
The present invention is a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen at a disease causing agent in combination with an immunostimulatory molecule for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms are provided using the recombinant virus.
La présente invention concerne un virus de recombinaison qui comprend dans son génome ou dans une partie de celui-ci un gène codant pour un antigène d'un agent provoquant une maladie, en combinaison avec un gène codant pour une molécule immunostimulatrice permettant de stimuler la réponse immunitaire contre l'agent provoquant la maladie. On décrit des procédés de traitement de maladies telles que le cancer ou des maladies provoquées par des micro-organismes pathogènes, utilisant le virus de recombinaison.
Moss Bernard
Restifo Nicholas P.
Rosenberg Steven A.
Department Of Health And Human Services The Government Of The United States Of America Represented By Th
Smart & Biggar
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