Enhanced migraine treatments based on ghrelin mimetics

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 31/00 (2006.01) A61K 31/4045 (2006.01) A61K 31/4164 (2006.01)

Patent

CA 2752813

The present invention relates to method of enhancing the absorption of migraine medications and thereby treating migraines by co-administering to a subject in need thereof an effective amount of a ghrelin mimetic or pharmaceutically acceptable salt, hydrate or solvate thereof and at least one migraine medication selected from a serotonin 5-HT IB/ID receptor agonist, a tryptamine derivative, an ergoline derivative, a non-steroidal anti- inflammatory drug, or an analgesic, or any combination thereof.

La présente invention concerne un procédé d'augmentation de l'absorption de médicaments contre la migraine et donc de traitement des migraines par co-administration à un sujet nécessitant celle-ci d'une quantité efficace d'un mimétique de ghréline ou un sel pharmaceutiquement acceptable, un hydrate ou un solvate de celui-ci et d'au moins un médicament contre la migraine choisi parmi un agoniste de récepteur de 5-HTIB/ID de sérotonine, un dérivé de tryptamine, un dérivé d'ergoline, un médicament anti-inflammatoire non stéroïdien, ou un analgésique, ou une combinaison quelconque de ceux-ci.

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