Enhanced stability phenylephrine liquid compositions

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2657611

An oral, liquid pharmaceutical composition is provided. The composition comprises phenylephrine and substantially aldehyde-free polyethylene glycol. The composition has phenylephrine stability compatible with the stability required for commercial preparations. Optionally, the composition may comprise one or more additional active agents.

L'invention porte sur une composition pharmaceutique liquide orale. La composition de l'invention comprend de la phényléphrine et un polyéthylène glycol sensiblement dépourvu d'aldéhyde. La phényléphrine comprise dans la composition de l'invention possède une stabilité qui est compatible avec la stabilité requise pour les préparations commerciales. Facultativement, la composition peut comprendre au moins un agent actif supplémentaire.

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