C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0784 (2010.01) A61K 31/195 (2006.01) A61K 35/30 (2006.01) A61K 39/00 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12N 5/10 (2006.01)
Patent
CA 2431080
Strategies are disclosed for generating dendritic cells that possess immune stimulatory activity despite immune suppressive factors elaborated by the tumor. An aspect of the invention includes blocking the arginase pathway in dendritic cells that are pulsed with tumor antigens. Alternatively, dendritic cells modified according to the invention are placed proximally near tumor tissues so as to naturally acquire tumor antigens and stimulate T cell responses. An object of this invention is to allow stimulation of Th1 immunity in cancer-bearing mammals that generally are predisposed to Th2 or anergic responses.
Na
O'brien Catherine Adele
LandOfFree
Enhancement of anticancer immunity through inhibition of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Enhancement of anticancer immunity through inhibition of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enhancement of anticancer immunity through inhibition of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1505390