Enhancement of antitumor therapy with hemoglobin-based...

A - Human Necessities – 61 – K

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A61K 38/42 (2006.01) A61K 47/48 (2006.01) C07K 14/805 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2185433

The use of hemoglobin-polymer conjugates to enhance antitumor therapy in mammals is disclosed. The methods include administering an effective amount of an antitumor therapy such as radiation in combination with hemoglobin conjugated to a substantially non-antigenic polymer.

On potentialise la thérapie antitumorale chez des mammifères en utilisant des conjugués à base d'hémoglobine. Ces procédés thérapeutiques consistent à administrer une dose efficace d'une thérapie antitumorale telle que la radiothérapie, en association avec de l'hémoglobine conjuguée à un polymère sensiblement non antigénique.

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