C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/67 (2006.01) C07K 14/805 (2006.01) C12N 1/38 (2006.01) C12N 15/31 (2006.01) C12N 15/54 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2072149
2072149 9106641 PCTABS00005 The invention related to a gene promoter/regulator (Region A in Fig. 1) which is useful in subjecting expression of protein or polypeptides in a host cell to selective regulation by external control. In particular, this regulation may be accomplished to different extends by the level of dissolved oxygen, presence of cAMP-CAP, and/or a complex nitrogen source in the culture or environment. The invention also relates to a method of improving production of proteins in a host by coproduction of hemoglobin in the host.
Bailey James E.
Khosla Chaitan S.
California Institute Of Technology
Smart & Biggar
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