C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) A61K 35/14 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2481406
A composition is disclosed that includes lin cells that are characterized as expressing CD31, CD34 and CD105, and not expressing c-kit, wherein the composition comprises fewer than 20% of lineage committed cells. Methods are disclosed for isolating CD31+CD34+CD45-CD105+c-kit-cells. Methods for reconstituting hematopoiesis using compositions including CD31+CD34+CD105+CD45- kit- cells are also disclosed.
L'invention concerne une composition qui comporte des cellules lin?-¿ qui expriment CD31, CD34 et CD105, mais qui n'expriment pas c-kit. Ladite composition comprend moins de 20 % de cellules déterminées pour une lignée. L'invention concerne des procédés permettant d'isoler des cellules CD31?+¿CD34?+¿CD45?-¿CD105?+¿c-kit?-¿, ainsi que des procédés permettant de reconstituer l'hématopoïèse grâce à des compositions comportant des cellules CD31?+¿CD34?+¿CD45?-¿CD105?+¿c-kit?-¿.
Fleming William H.
Li Bei
Oregon Health & Science University
Smart & Biggar
LandOfFree
Enhancement of hematopoietic stem cell survival does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Enhancement of hematopoietic stem cell survival, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enhancement of hematopoietic stem cell survival will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2027799