Enhancement of morphogen activity

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/70 (2006.01) A61K 31/47 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2307826

The present invention provides methods and compositions for enhancing morphogen activity in mammals, including humans. The methods involve the administration of a molecule capable of releasing morphogen inhibition. The molecule can be administered either alone or in combination with a morphogen. The present invention further provides screening methods for indentifying a molecule capable of enhancing morphogen activity.

La présente invention concerne des procédés et des compositions permettant d'améliorer une activité morphogène chez les mammifères, y compris chez les humains. Ces procédés consistent à administrer une molécule capable de libérer l'inhibition morphogène. Cette molécule peut être administrée seule ou en combinaison avec un morphogène. La présente invention concerne, en outre, des procédés de criblage permettant d'identifier une molécule capable d'améliorer une activité morphogène.

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