A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/00 (2006.01) A61B 5/055 (2006.01) A61K 49/18 (2006.01) G01N 24/08 (2006.01) G01R 33/28 (2006.01) G01R 33/46 (2006.01) G01R 33/465 (2006.01) G01R 33/48 (2006.01) G01R 33/483 (2006.01) G01R 33/62 (2006.01)
Patent
CA 2250401
The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
La présente invention, qui concerne généralement les techniques de résonance magnétique nucléaire (RMN) appliquées aussi bien à spectroscopie qu'à l'imagerie, concerne plus particulièrement des procédés dans lesquels on utilise des gaz nobles (par exemple le xénon et l'hélium) hyperpolarisés pour renforcer et améliorer la RMN et l'IRM. En outre, les solutions de gaz hyperpolarisés de l'invention conviennent particulièrement pour l'étude, aussi bien in vitro qu'in vivo, de la dynamique ou de la structure d'un système. Dans le cas des systèmes biologiques, in vivo ou in vitro, l'invention consiste à cibler le gaz hyperpolarisé et à l'apporter dans des régions spécifiques à l'intérieur du système.
Appelt Stephan
Bifone Angelo
Budinger Thomas
Goodson Boyd
Navon Gil
Fetherstonhaugh & Co.
Lawrence Berkeley National Laboratory
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