C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/079 (2010.01) A61K 35/12 (2006.01) A61K 35/30 (2006.01) A61K 38/19 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2527847
The present invention is generally in the field of neurological diseases and disorders, particular in the field of neurodegenerative diseases in which the myelin cover of nerves is lost. IL6R/IL6 chimera is used to promote the formation of oligodendrocytes from embryonic stem cells for treatment of neurodegenerative diseases or posttraumatic nerve damage.
La présente invention concerne, d'une manière générale, le domaine des maladies et des troubles neurologiques, en particulier le domaine des maladies neurodégénératives dans lesquelles la couverture de myéline des nerfs est perdue. Une chimère IL6R/IL6 est utilisée pour promouvoir la formation d'oligodendrocytes à partir de cellules souches embryonaires pour le traitement de maladies neurodégénératives ou d'une détérioration nerveuse post-traumatique.
Chebath Judith
Lonai Peter
Revel Michel
Borden Ladner Gervais Llp
Yeda Research & Development Co. Ltd
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