Enhancers for the transdermal flux of certain...

Details Enhancers for the transdermal flux of certain... Enhancers for the transdermal flux of certain...

A - Human Necessities

61

K

167/208, 167/228

A61K 9/06 (2006.01) A61K 31/44 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/18 (2006.01)

Patent

CA 1305419

30,501 ENHANCERS FOR THE TRANSDERMAL FLUX OF CERTAIN 1,4-DIHYDROPYRIDINE DERIVATIVES ABSTRACT The transdermal flux rates of 1,4-dihydropyri- dine derivatives, such as nilvapidine and its enantiomers may be increased by the use of a solvent vehicle which comprises dioctyl adipate, isopropyl myristate, benzyl alcohol, diisopropyl adipate, a mixture of 5 to 50% ethyl alcohol and 95-50% of diisopropyl adipate, or a mixture of any of the foregoing.

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