Enhancing immune responses to genetic immunization by using...

A - Human Necessities – 61 – K

Patent

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A61K 39/00 (2006.01) A61K 39/29 (2006.01) A61K 39/39 (2006.01) A61K 48/00 (2006.01) C12N 15/36 (2006.01) C12N 15/49 (2006.01)

Patent

CA 2326685

The immune response to a DNA immunogen in a mammal can be enhanced by administration of a chemokine or a polynucleotide encoding the chemokine. This method can be used, for example, to immunize or vaccinate a mammal against an infectious disease or a tumor.

La réponse immunitaire à une substance immunogène de l'ADN chez un mammifère peut être améliorée par administration d'une chémokine ou d'un polynucléotide codant ladite chémokine. Ce procédé peut être mis en oeuvre, par exemple, pour immuniser ou vacciner un mammifère contre une maladie infectieuse ou une tumeur.

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