Enhancing the immune response to an antigen by...

A - Human Necessities – 61 – K

Patent

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A61K 39/39 (2006.01) A61K 31/7088 (2006.01) A61K 39/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/705 (2006.01) C12N 15/863 (2006.01)

Patent

CA 2394597

A method of enhancing an immune response is disclosed. The method involves an initial priming of the animal with an inducing agent, subsequently followed by administration of an inducing agent-antigen mixture. The antigen may be a tumour associated antigen, pathogenic organism antigen, autoimmune antigen, immunogenic fragment thereof, or a nucleic acid coding therefor.

L'invention concerne un procédé d'amélioration de la réponse immunitaire. Ce procédé consiste à assurer l'amorçage initial sur animal avec un agent d'induction, avant d'administrer à cet animal un mélange d'antigène et d'agent inducteur. L'antigène peut être un antigène associé à une tumeur, un antigène d'organisme pathogène, un antigène auto-immun, un fragment immunogène de ce dernier ou un acide nucléique codant pour ce dernier.

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