Enkephalinase and endorphinase inhibitors as anti-craving...

Details Enkephalinase and endorphinase inhibitors as anti-craving... Enkephalinase and endorphinase inhibitors as anti-craving...

A - Human Necessities

61

K

167/258

A61K 31/195 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1321146

ABSTRACT OF THE DISCLOSURE A new class of anti-craving compositions is provided by including, in such compositions, substances which inhibit the destruction of neuropeptidyl opiates. In one aspect, an anti-craving composition is provided by including, in such compositions, substances which inhibit breakdown of endogenous substances, e.g. enkephalins and/or endorphins. An anti-alcohol craving effect is observed with an enkephalen breakdown inhibitor. Specifically, D-phenylalanine, DL-phenylalanine, D- leucine, DL-leucine, and hydrocinnamic acid, each an encephalin breakdown inhibitor, significantly lower alcohol intake in animals and humans. The anti-alcohol desire effect is observed in animals genetically prone to choose alcohol over water solutions.

570317

Affiliated with

Also associated with

Rating

Enkephalinase and endorphinase inhibitors as anti-craving... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enkephalinase and endorphinase inhibitors as anti-craving..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enkephalinase and endorphinase inhibitors as anti-craving... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1172400