Enrofloxacin injection or infusion solutions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/495 (2006.01) A61K 31/19 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2210076

The present invention relates to novel injection and infusion solutions of the following composition: a) 0.1 to 20% by weight of enrofloxacin, based on the total weight of the solution, in the form of its salts with polyhydroxycarboxylic acids or amino acids or mixtures thereof, b) polyhydroxycarboxylic acids, amino acids or mixtures thereof in 0.1 to 5 molar excess, based on enrofloxacin; c) optionally 0.1 to 30% by weight of formulation aids, based on the total weight of the solution; d) water to 100% by weight.

La présente invention concerne de nouvelles solutions d'injection ou de perfusion dont la composition est la suivante: a) 0,1 à 20 % en poids d'enrofloxacine par rapport au poids total de la solution sous forme de ses sels avec des acides polyhydroxycarboxyliques ou des acides aminés ou bien leurs mélanges; b) des acides polyhydroxycarboxyliques, des acides aminés ou leurs mélanges en excès molaire de 0,1 à 5 par rapport à l'enrofloxacine; c) éventuellement 0,1 à 30 % en poids d'auxiliaires de formulation par rapport au poids total de la solution; d) de l'eau pour totaliser 100 % en poids.

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